The un-controllable yearning and craving for food that overwhelms your body rendering you useless until the craving is satisfied. Usually the normal list to survive is air, water and food. In a Super-mighty-munchies episode you need food, air and then water. To satiate the super-mighty-munchies you must consume snacks of a salty, sweet or crunchy nature until the craving recedes.
A teenager, awake at 2am is gripped by a Super-mighty-munchies episode and eats an entire box of cinnamon toast crunch before his state of mind and hunger returns to normal levels.