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2.
A way of expressing somthing which is blatantly true to his or her fellow man through a clenched fist in the shape of a vertically upright 'respect' hand gesture. It's also one of the greatest ways to see who will agree with you on a particular point or if somthing is so obviously true that it must be expressed to ones peer.
Bredin Number 1: "Our teacher is so moist alie?"

Bredrin Number 2: "Spud me on dat fam!"
by Ricky C You Get Me? February 28, 2011
 
1.
Alternative greeting phrase for endearment. Usually said whilst holding out a closed fist, similar to saying "safe".
Person X: Safe blud, you good?
Person Y: Yes, spud me.
by zingermeal September 06, 2008