When someone has every orifice, hole, crack and crease in/on their body filled with semen. Generally in reference to a megawhore, super slut or uberskank.
My neighbor is a true multi-tasker. She'll take it everywhere and from everybody. That girl leaves no hole unfilled. She's spooge-spackled up to her eyelids!!
Make sure to fill in every hole in his body. This boy needs to be spooge-spackled before the night is through...
That girl is a spooge-spackled princess aint she?