Top definition
A disease which entails a group of people who unknowingly talk about spongebob or make spongebob references daily or more.
Person 1: Omg a police officer is coming, act natural
Person 2: Mooooo
Person 1&2: Spongebob Diseaseee!

Person 1: I am sooo thirsty
Person 2: Some Waterrrrr would be nice.
Person 1&2: Spongebob Diseaseee!

Person 1: Let's order pizza
Person 2: Krusty Krab Pizza, is the pizza for you and me!
Person 1&2: Spongebob Diseaseee!
by Cannibitch <3 March 23, 2010
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