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1.
Sprio Agnew is an anagram for "Grow a penis".
Spiro Agnew bitch and I'll knock you down.
by MackDaddyLove October 11, 2005
 
2.
Richard M. Nixon's vice president. Resigned in 1973 due to scandal. Coined such phrases as "nattering nabobs of negativism."
Spiro Agnew thinks you're all pusillanimous pussyfooters.
by Albie Wangsta April 01, 2004