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Derived from the "Spidey sense" of the comic book superhero Spiderman, it is generally used to mean a vague but strong sense of something being wrong, dangerous, suspicious, a security situation.
He looked like a student, but something about his dirty shoes and the way he tried to open a locked door totally set off my Spidey sense, so I called campus security.
by JohnnyHoffa March 23, 2008
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2
A vague but powerful sense of danger or creepyness based on intuition.
1) I told that woman I felt a instant connection to her and that I knew we were soul-mates. Then I asked for her number but the gal's spidey sense must have been tingling because she just stood right up without saying anything and got off the bus.

2) That lady's spidey sense must have been working overtime that day because as soon as I started talking to her she gave me one of those "I'm about to start screaming" faces and then moved to another seat at the far end of the subway car.
by misunderstood guy March 08, 2009
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3
The freakish sixth-sense imparted on Peter Parker (AKA:Spiderman) after being bit by a radioactive spider.
Dude, let's go ask those chicks to dance. My spidey sense tells me, they will put out.
by Goldblogger August 16, 2005
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4
Extra-defined senses in a human.
You heard me blink? Dude, you have spidey senses.
by Tayfunn August 07, 2008
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5
The hightened ability to smell weed. An ability that stoners gain over time to detect other stoners in public.
So then he went and... *sniff* ... my spidey sense is tingling.
by lumpkin face April 09, 2006
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6
a sense that you gain once you have become an experienced pot-smoker. This sense is an enhancment of your sense of smell which allows you to detect the smell of marijuana from extreme distances in extreme conditions.
yo, you smell that, my spidey sense is tingling!
by lumpkin face March 25, 2006
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7
The ability to win a prize by scratching the corrent web.
"Play the spidey sense game on this cup, and win a KING SIZE VALUE MEAL!"
by Sarah J <sarizzle> July 21, 2004
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