one of the most unique fantasy anime I've seen (another being Hetalia), it involves around the adventures of Kraft Lawrence (a traveling merchant) and Horo (a wheat deity). The stories involve trade back in the medieval/renaissance era, it explains a lot of the workings of it, along with some historical references. However if you're an action oriented anime lover you'll probably won't be watching this.
guy 1: what are you watching?
guy 2: Spice and Wolf
guy 1: you should watch BLEACH instead, it's so much better
guy 2: I've been watching that a bit too much lately and would rather take a more laid back one that has some need of thinking more than action.
guy 1: suit yourself