Top Definition
A friend who you are very close to and see and talk to almost everyday; it's as if they were your brother or sister; they are like family to you.

Your personalities match perfectly and you get along very well. You can tell them anything and they can tell you anything. Your souls are in sync.

Similar to brother from another mother or sister from another mister but no relatedness is implied.
1) Craig and Danielle are my soul siblings.
2) You see that guy over there, he is my soul sibling.
by friendsfreak1989 November 04, 2010

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