1) A woman who lives, works, or exists in the SoHo neighborhood of Manhattan. Typically wealthy, well-dressed, and not very bright.

2) A woman who will do anything to advance in the art world.
1) While in NYC, beware of SoHoes wearing silly hats from fc*uk.

2) I can't believe Sara sucked off that guy just so she'd get her own gallery. She's such a SoHoe!
by Jordan March 13, 2006
Sorority hoe
Dude, there are like 12 sohoe from (insert sorority name here) that are dtf!!! I love a good sohoe!!!
by Fepic Bros December 18, 2010

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