Etymology: New Latin, from Latin, detergent, soap, from Greek smEgma, from smEchein to wash off, clean
: the secretion of a sebaceous gland; specifically: the foul-smelling pasty, cheesy sebaceous accumulation of desquamated epidermal cells and sebum that collects in moist areas like between the glans penis and the foreskin or around the clitoris and labia minora.
circumcised.' I like it! It's my cheese! Give it to me!"
Howard Stern, talking about smegma, on his radio show, 4/11/00
Side note: While smegma may be reminiscent of a domestic cheese, ball sweat smells like mayonnaise!