With Skittle bag, sometimes used to refer to miscellaneous heterogeneous mix of various narcotic pills, jumbled up in a bag (usually leftovers donated to the communal skittle bag). Often multicolored like a bag of skittles. Incredibly dangerous, as the actual contents are often unknown, and, thusly, the effects are often a surprise high.
Yo, break open the bag o' skittles and let's do some lines.
by captain phoenix May 09, 2006