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1.
The angels of the Boston Latin School.
(usually short asian nerds -cough- sometimes ghetto black kids)
Mr. Harrytoes: I'll give you 100R for each cockroach you find.
Sixie A: Let's go cockroach hunting!
Sixie B: YAHH WE COULD TOTALLY THROW SOME COCKROACH TRAPS HERE AND THERE!
Sixie C: Or we could just go out and buy some...
Sixie A+B: STFU o-o;
by JBoogii2013 July 10, 2008
 
2.
Someone who has six more years of school to go. A seventh grader. Term namely used at Boston Latin School. Can be a term of affection or an insult, or if you don't know the name of someone in the seventh grade.
Upperclassman: Hey, sixie, do you have Haritos for science?
Sixie: Yeah, I'm in Cluster A!
Mascot: GO WOLFPACK!
by ebkf May 01, 2005