When you blatantly diss or call out somebody you have a disagreement or problem with. stems from the term "Warning Shots"
Guy 1: Oh, he's just mad at me because I had sex with his girlfriend.
Guy 2: OH SHIT, SHOTS FIRED!
by He Who Is Awesome September 07, 2009
(Interjection) - A reply given directly after a person gives a witty remark or serious burn.
Person A: *super hot burn*
Person B: Shots Fired!
pow pow
*pow pow*

(sound of a gun firing shots)

Shots Fired
by Ching chong engrish November 17, 2013
When you shotgun a beer, and then take a shot of fireball. The first person to finish both drink and yell "Shots Fired" wins
Man I was so drunk after playing Shots Fired
by John Cheadle March 08, 2014
what you say after you fart/ blow a hole in your chonies; replacement for "safety"
johnny: "shots fired"
timmy: "you got fart particles on my chorizo!"
by lilbigmouth June 27, 2010
When u hide in the dark and hold your breath for like wayyyy to long
"Hey buddy, are you asleep or somethin? whatchya doin, "
"Im holdin' my breath an sittin in the dark cause I heard 'Shots fired - Shots fired'!!
by Jayare a.k.a. goo1z August 22, 2009

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