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1.
The perfect level of drunkness, falling between shitfaced and tipsy.
Would you Like another beer, sir?

No, I'm feeling pretty shitsy.
by Me Animal December 10, 2010
 
2.
"adj" As to or referencing a case of the "shits" or runny bum syndrome. "noun" Or a term of endearment for a piece of shit car.
I ate 20 jalepenos and drank a fifth of tequila and boy oh boy do I feel shitsy!

Have you seen my new Subaru? She's my shitsy and I love her.
by Ben MP October 20, 2007