Sayers means downie, if your nickname or name is Sayers, you might want to get the one way bus to the edge of the earth (assuming the earth is flat.. it's not but, that's what Sayers thinks)
Scene kid: Hey Sayers!
Sayers: Mleh ma ma ma noaar
Scene kid: What?
Sayers: Mlaah masaa muuummllaa
Describing a gay person, with no friends who no one likes. Someone who is Sayers, is annoying as hell and you would do anything to get rid of them.
Dave: No one likes me
Jim: That's because your a Sayers.