Top Definition
Nickname for House Speaker Nancy Pelosi (D-CA) whose district encompasses San Francisco. Used frequently by conservative talk radio host Laura Ingraham.
The San Fran Gran Nan made a statement from the House floor preaching to Americans that they must conserve energy. She then took a limo to the DC airport and flew to San Francisco in her private jet.
by John1971Hou November 08, 2009
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