Top Definition
SPU
Origin: Internet / Instant Messaging

Variation of the word "SUP". Meaning "Whats Up?"

Typing fast and frequent mispellings lead to this more lively version of "SUP"
Bob: Spu!
John: Hey!
by Grizzly October 06, 2004

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SPU
Short for “Sound Processing Unit” – sound card.
I just bought my new Creative SPU and mounted it in my PC.
by Faalagorn February 15, 2008

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spu
the emission of jizz, cum or sperm; to emit an organic fluid known as semen that usually contains spermatozoa; The process of discharge called ejaculation.
I'm gonna spu my load all over that hottie.
by candygirl69 October 20, 2010

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SPU
Small Penises United!!!
Nate and Jake are apart of SPU
by Smallpenis1.5 March 11, 2010

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The Urban Dictionary T-Shirt

Soft and offensive. Just like you.

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The Urban Dictionary T-Shirt

Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).

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