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1.
A reference from ilovebees (Halo)

SPDR (System Peril Distributed Reflex) is a reactive emergency twitch encoded holographically into the fabric of top-tier ONI AIs
If an AI gets damaged its the job of the SPDR (itself a low level AI) to perform system repairs.
by Redsmartie November 23, 2004
 
2.
Suck Penis and Die Retard

i.e. Spdrman (commonly referred to as a guy who sucks dick) or Spdrwoman (a Gal) Usually a moniker of the classic superhero Spiderman.
That guy is Spdrman, he likes his sausages big!
by Ghettoz September 10, 2003
 
3.
Suck Penis and Die Retard
SPDR you worthless homo!
by Charlie September 05, 2003