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3.
Serious lack of skill, used in the gaming world.
Eg: That guy has some major slos issues!
by Olli Sorsamo June 27, 2007
7 6
 
1.
SLO
San Luis Obispo
Cal Poly SLO
by Irie April 10, 2003
245 85
 
2.
A very Good Thing Indeed. From the expression 'Skins Left On' i.e. full of goodness.
A more up to date version of FTW!
Peanut Butter Sanwiches SLO!
by multiplication September 11, 2008
4 3
 
4.
SLO
Silently Laughing at the Office
Jen was SLO over the LOLCat Ben had sent her
by AstridBF May 31, 2013
2 3
 
5.
slo
San Luis Obispo, California
A city comprised of only stuck up, rich white kids whose parents buy them whatever they want and support their drug and alcohol problems.
I love SLO because it is so white-bred
by I heart Cal Poly April 10, 2004
135 149
 
6.
slo
a mix between slut and ho. another term for slore
person 1: did u hear brittney slept with that senior last night?

person 2: that slo!
by flyingchinchilla April 16, 2011
6 24
 
7.
Slo
The cross between a slut and a ho
The slo tried to steal my man.
by Janelle and Stephaine January 04, 2003
26 83