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1.
S/E
S/E: Save And Exit. A word meaning to Quit, Giveup, Your Garbage, You Suck, Noob.
My new acronym: S/E "Save And Exit"

Meaning, Quit, Giveup, Your Garbage.

Used in the gaming community.
by Fogles July 23, 2006
 
2.
s/e
Easy Way For Cool Kid To Tell Save And Exit In The Game Diablo 2
Omg I own you noob , s/e plz
by FrogZor July 11, 2006
 
3.
s/e
Simply put, it means "Self-explanatory"
james56: wuts 'eat shit' mean?
markfark: its s/e

student: once u go 2 TurnItIn.com 'n enter the info, turning n ur paper is s/e
by funkeywoookey March 24, 2008