look up any word, like turnt:
 
1.
"We're no strangers to love
You know the rules and so do I
A full commitment's what I'm thinking of
You wouldn't get this from any other guy

I just wanna tell you how I'm feeling
Gotta make you understand

Never gonna give you up
Never gonna let you down
Never gonna run around and desert you
Never gonna make you cry
Never gonna say goodbye
Never gonna tell a lie and hurt you..."
rotfl, Rick Roll'd!
I enforce rule 101!
OMGWTF! Rick roll'd again!
by I.Anonymous November 24, 2008
 
2.
When a topic being discussed on an IRC channel degenerates into memes and cliché's, Rule 101 is called to automatically end the current topic and start a new one.
Guy 1: No u
Guy 2: NO U
Guy 1: O rly?
Guy 3: Rule 101.
Guy 2: lol
Guy 1: oshi-
by nommyface1 April 30, 2010
 
3.
If your are ugly you do not exist.
"Dude" -Im an ugly stupid emo faggot!
"Other dude" - No need to worry, by rule 101 you do not exist
by John F. Ucking Smith May 29, 2008