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1.
The act of a female pretending to be drunk so that a male will take advantage of her. In essence, this is when a female needs an excuse to sleep with someone, but her friends most likely do not approve.
1. "She pulled a reverse-roofie so she could get with him."

2. "That biddy just reverse-roofied him!"
by McClubbin dutch November 25, 2011
 
2.
Giving someone caffeine so that he or she parties harder and longer.

I write he mostly in jest because no man has ever been roofied for the purposes of date rape, ever.
Man those hot chicks were acting all lame before and wanting to just sit around. So I grabbed some Four Loko and the reverse-roofie cocktail and got the party started!
by moneycashdane May 02, 2011