To make someone or something retarded, or of lower functionality than it was prior to its retardification.
ex1: I just can't bring myself to talk to that hot girl. Every time I get close to her I get retardificated.
ex2: I dropped my laptop yesterday, and now it's all screwed up and retardificated!
To make retarded; the act of making one mentally ill; to mentally slow one or more peoples
Tom was going to retardificate Sam but he wimped out and played runescape instead.