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Brotha Lynch Hung's hit from the 1995 album "Season of da Siccness" Used as a universal insult for "tellin' some nigga that he ain't shit, and he can go to hell" or as a friendly gesture of farewell to a friend. "rest in piss man, ill see you later"
ex.1 Insult

"That mother fucker can rest in piss!"

ex.2 Goodbye

Franklin- "Peace Mike, Ill see you later"

Michael- "Later Frank, rest in piss"
by restinpissnodoubt November 11, 2010
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