The name has a spiritual, not literal meaning, i.e., to be born again with baptism, i.e, from water and the Holy Spirit). It was extensively adopted by early Christians in Ancient Rome, due to the importance of baptism. The onomastic is San Renato, a martyr, Bishop of Sorrento in the 5th century, which is celebrated on December 12.
In Persian Mithraism, which spread widely in the West as a religion of the soldiers and officials under the Roman Empire, persons initiated into its mysteries were designated renatus (with the meaning of regenerated).
Publius Flavius Vegetius Renatus, Later Roman Empire writer (4th century)
Renatus Profuturus Frigeridus, historian (5th century)
Renatus of Châlon (1519–1544), Prince of the House of Orange
Renatus Harris (ca. 1652-1724), English master organ maker
Renatus Cartesius (1596–1650), also known as René Descartes, French philosopher, mathematician, scientist and writer