The noise males (typically British and American males) make when they see something uberly awsome.
Stew - hey, Dan, isnt that Chuck Norris spanking Bin Laden?
Dan - OMG!! IT IS!!
Dan and Stew - QUWEE!!!
A mix of cool and sweet, two words I often mix up and it always comes out as Quwee
guy 1:"OMG I just saw Wesley Snipes taking a dump"