Skewed, messed, fowled, or fucked up. Broken or nonfunctional. Ruined, tainted, or changed....As in test results that are messed up; whether by accident, or deliberate action. Also any mechanical device or machine that is broken, or non functional for similar reasons.
1. "These test results are completely queered".
2. "This engine is totally queered, dude".
3. "You've really queered this whole party by inviting your jerk-off brother".