It means to play a game you are ecceptionally good at online against other people. An example would be Call of Duty Modern Warfare 2. You can only say this of course if you are actually capable of pwning noobs.
Guy 1: Hey you wanna pwn the noobs with me later?

Guy 2: I was just pwning the noobs like half an hour ago, I'll play tonight.
by the master bator 01 February 27, 2010

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