Top Definition
The act of running into a bar bathroom needing to vomit, proceeding to open a stall door and projectile puke directly onto someone who is taking a crap. Then, punching them in the face to eliminate the possibility of any retaliation.
"Dude we gotta go...like right now" "Why?" "I just Puke Dukem'd a guy in there, we don't have much time."
by prythirdeye November 06, 2011

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