Top Definition
Where you play 'Pro Evoultion Soccer 6' so much that when you play real football it feels like your playing the game. You may even say the button you would press while doing the corresponding move!
Jerd and James were playing football in the park

Jerd: Yes, on your 'ed, James!

James: Yes....use the circle button!

Jerd: Gee James, you have Pro Syndrome
by Samyall May 15, 2007
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