Top Definition
The swelling of the part of your brain that makes you do stupid, loud, and/or destructive things. Usually as a result of residing in Pritchard Hall, the largest all-male dorm west of the Mississippi.
Goddammit, I just broke (insert expensive possesion here)!.. my pritcharditis is acting up again.

"Ahhhhhhhhhhh, mutha fucka!" 'What the Hell was that?' 'Probably just pritcharditis...'

Man, someone cut the brand-new big screen tv! effin' Pritcharditis...
by Buttamilk February 16, 2006

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