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1.
A remedy or cure for what ails you

A solution to the problem

Usually a term for medically prescribed drugs
The best prescription for pain is being outdoors, taking time to "smell the roses", watch the hummingbirds outside your window & Love with all your heart!
by Morphologicalfreedom... September 28, 2013
 
2.
Getting some damn good road head. Rx = RoadHead Extreme.
Damn, that bitch filled my prescription awful fast, kinda like your mom.
by delorise December 27, 2005