Top Definition
A condition where women are not interested in a man's willy unless he can keep her in Prada. Epidemic in some parts of London.

Not to be confused with Prader-Willi syndrome - http://www.thearc.org/faqs/pwsynd.html
"I think my luck's in there, mate."
"No chance. She's got Prada-Willy syndrome, she has."
by Cheesewhiff January 16, 2006

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