Top Definition
The depression sometimes felt after sexual intercourse or masturbation.
Jonathan suffered from post-coital depression this morning after cumming his balls, brains and spinal fluids out last night in an orgy of procrasturbation.

After losing her virginity in an orgasm filled, yet loveless bangathon in her dorm room last night, Dafny felt a mixture regret, post-coital depression and vaginal soreness.

News that his baby tank was pregnant again with more fuck product only deepened Harry's weeks long post-coital depression.
by AYYFRON October 19, 2009
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