Top Definition
The magical potion used in Harry Potter to change the physical appearance of one human to another using part of their DNA.

The stuff that dreams are made of. And shapeshifters.
I took some Polyjuice Potion and magically turned into Justin Bieber!" "You can leave now.
by The purple-pointed toothy-toes January 23, 2011

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The Urban Dictionary Mug

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The Urban Dictionary Mug

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