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1.
Meaning filled with angst, or of/relating to Edgar Allen Poe, this word originated with art school dorks and eventually made it's way to inner city street gangs.
"Bro, that mothafucka is Poe'd up! Look at his eyeliner!"
"He ain't Poe'd up, mein! He's just a fag!"
by Johnny November 17, 2004