This word refers to a man who has attained such a level of sexiness and manliness that he can even exude sensitivity without coming across as gay. Someone who is referred to as picoli must be incredibly sexy, virile, and have an affinity for Tom Cruise movies.
Male or Female: Shit that guy is so sexy and manly without being overbearing while epitomizing greatness in every sense.
Male or Female #2: Damn, he soooo picoli!!