Top Definition
Any asshole driving a pickup truck engaging in behavior becoming someone associated with this pejorative; broadly, the vast majority of those driving pickup trucks.
Man 1: I had to jam on my breaks because that guy up ahead pulled out on me at the last second even though there was no one behind me for a mile. He then proceeded to drive 30 in a 45 zone.

Man 2: Yup, major pickup fuck.
by TOAOR September 13, 2011

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