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1.
From 'Perpetrate' - The act of commiting a serious wrong against another. *Please Note* Also may be classified by Degrees from 1-3 (with 1 being the worst).
"I can't even believe that ho slept with my man...that is a PERPETRATION!"
Or with degrees
"Oh no she did not wear those raggedy a$$ shoes, that is a perpetration in the 3rd degree."
by Angela A. April 07, 2005
 
2.
To plan, create, and carry out a sheer abominable act
"Perpetration's been really heavy tonight."

"Did you witness the perpetration going on in that car?"
by nunnyduh July 06, 2010