Top Definition
A show starring Pee Wee Herman. A very bizzare show aimed torwards young children, but actually has various sexual meanings behind it.

This show replaced Mission Hill on Adult Swim in 2007. This is the show that many people go find something else to do when it's on, and wait for a better show like family guy to come on.
Pee Wee's playhouse is not cool.
by Pee Wee's playhouse July 10, 2008

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