Top Definition
Like adrenaline, party sauce is what runs through your veins when you know it's time to party.
"I've got the party sauce in me tonight, brah."
by Big Dik Dollaz May 08, 2008
when you mix ketchup and mayonnaise. It is so good you feel a party going on in your mouth, hence "party sauce".
"Bruh have tried party sauce?"

"ketchup and mayo? that shit is dope"
by baechesterman March 14, 2016
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