Top Definition
A person born in the United States of Mexican descent and of descent from the Paisa Region of Colombia (Antioquia, Colombia).
My dad is from Medellin, Colombia, and my mom was born here, but she is Xicana (her parent are from Mexico), so I am a third generation Mexican, but I am a Paisa too from my dad's side, therefore I am a Paisa Xicano.
by jhonface. July 28, 2009
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