Top Definition
PMSFL - Pre Menstrual Syndrome's Fucking Leathal

P - Pre
M - Menstrual
S - Syndrome's
F - Fucking
L - Leathal
Recurring cycle of psysiologic changes that occurs in reproductive age females.
Take your hands into your own life if you go near a female at this fucking time of the month, run like fuck or your a dead man.

PMSFL can also mean Pissin Myself Fuckin Laughin LOL
by TERRIFIED MALE February 27, 2008

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