Top Definition
A Mexican-American lawyer, political activist, writer and drug fiend who is best noted for hanging out with Hunter S. Thompson in the late 60s and early 70s. Acosta disappeared while on a trip to Mexico in 1974 and whos where-abouts are to this day unknown. He is presumed dead.
That Oscar Zeta Acosta was one messed up dude man.
by Ron Thonrbrash August 01, 2005

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