When your penis is so infested with syphilltic, itchy sores that you cut it off in a fit of rage. A reference to Oren Ishii, a character in Kill Bill who cuts off someone's head in a fit of rage.
"Sorry, girl, but I can't give you any tonight. I couldnt take it anymore, so I went Oren Itchy last night."
by Shrug February 01, 2013