Orange and Blue refers to bar areas that is full of people from outside DC proper. They are called "Orange and Blue" because those are the metro lines that bridge No. VA into DC.
"What's good this tonight?"

"I was thinking of heading to U Street, but it's so Orange and Blue on the weekends."
by Phillip Pino April 19, 2010
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The seven colors of the rainbow, also the same colors of the pride flag for LGBTQ.
Dude 1: What are the colors of the rainbow.
Dude 2: Umm.. it's red orange yellow green blue indigo violet.
Dude 3 in the corner: HAHA! YOU GAY!
by BlackSoul659 March 5, 2022
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To do the impossible or to make a desperate situation turn out into something good.
His business was about to go bankrupt and nobody expected anything, but with his last money, he got a business coach, who helped him to orange the blue. 5 Years late his company sold for $3 billion.
by NeologisticPie February 1, 2020
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