look up any word, like lemonparty:
 
1.
The physical, mental, and emotional condition one achieves through prolonged periods (generally multiple consecutive days) of sleep deprivation, malnutrition, & dehydration while under the influence of methamphetamines. Symptoms vary among individual users. However, common effects are delirium, schizophrenia, irritability, anxiety, mood swings, irrational & compulsive dis-assembly of household appliances & devices, chronic back & neck misalignment, and ill-advised barter of personal possessions (not necessarily belonging to the one affected by the condition).
The scatter-brained tweaker was obviously on a good one as he carpet surfed his car & sifted through the vacuum bag for meth on day five.
by Llenar13 January 30, 2010
 
2.
the same as on one but for a longer period of time. i.e. five or more days.
He would have outran the cops but he was on a good one and it finally caught up with him.
by brandon's wife May 21, 2004
 
3.
to be really hyperactive usually enhanced by stimulants (caffeine, sugar, chocolate)
lil monster is on a good one
by skaterjack October 05, 2006
 
4.
To be sexually stimulated to the point you want to have sex.

When the penis gets hard from a male thinking dirty thoughts and this make him want to fuck. The vagina hardens when a female thinks naughty and this makes her want to fuck.
Say whodie, my girl had me on a good one last night.

Girl my boyfriend had me on a good one earlier today when we were on the phone.
by Kietee025 June 25, 2006