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1.
A phrase used to articulate feelings of immense loathing of someone that is known for unintelligent or troublesome actions. The phrase being used when a particular action comes into play. Usually followed by a facepalm.

Origin: First used in season 4 of "Futurama", episode 68 - "Obsoletely Fabulous". Bender, because of his new found hatred for advanced technology, has had a downgrade, making him a wooden, steam-powered robot. Bender enters the scene and Leela immediately exclaims "Oh brother, he's made of wood."
Leroy: "Is that Clyde over there?"

Jeff: "Dammit, I think so. What's he up to this time?"

Clyde: "Hey Jeff! Check it out! I found this guy down at the hospital on 42nd street! He seems pretty cool! Check out his cool bracelet!"

Leroy: "Isn't that 'hospital' a personal care home for the mentally ill?"

Jeff: "Oh brother, he's made of wood."
by Colt Guthrie July 09, 2010