Top Definition
When you are in a room (office, classroom, etc.) without an attractive person, so you choose someone that you can pretend is attractive just for the sake of having someone to oggle at.
Jade: "Wow, Marla. That guy over there is super hot!"
Marla: "Uh... Dude, I think you have a severe case of Office Syndrome."
by J1tt3rbug June 26, 2012

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