To go crazy. To run amok in an urban sense. To take something to an extreme level.
Dude buys a bag of weed. When he gets home he discovers its oregano, a burn bag. He tears up the bag. Kicks over a chair. Punches a hole in the wall while vowing revenge. His girlfriend is cowering in the corner. She hits her sister up on her cell, telling her, "Get over here and pick me up. He's going 'off bucks!'"